Bicaval vs biatrial anastomosis techniques in orthotopic heart transplantation: An updated analysis of the UNOS database.

BACKGROUND: Despite the significant increase in the number of orthotopic heart transplants (OHT) performed yearly using the bicaval anastomosis technique, the impact on long-term outcomes remains a topic of debate. We analyzed the United Network for Organ Sharing (UNOS) database in search of the latest insight. METHODS: We performed a retrospective analysis of the UNOS database from 2006 to 2016 to identify first-time OHT recipients. Patients were primarily stratified according to anastomosis technique: bicaval vs biatrial. Baseline characteristics and clinical status were recorded. The primary endpoint was all-cause mortality. Secondary outcomes included need for permanent pacemaker (PPM), and length of hospital stay (LOS). The Kaplan-Meier method was used to compare survival between the two groups. The Cox proportional hazards regression model was used to conduct multivariable analysis. Statistical significance established at P < .0001. RESULTS: A total of 26 990 patients were identified. Of those who met the inclusion criteria (21 597), 16 573 (77%) underwent bicaval anastomosis. There were no major differences in baseline characteristics between the two groups. The bicaval anastomosis technique was not associated with increased survival during the study period (hazard ratio: 0.97; P = .3557), but the bicaval group required postoperative PPM less often (2.51% vs 5.79%, P < .0001) and was associated with shorter LOS on multivariable analysis. CONCLUSIONS: The use of either bicaval or biatrial anastomosis during OHT offers comparable survival advantage. Nonetheless, bicaval anastomosis is associated with less need for postoperative PPM and slightly shorter LOS.

Prótesis de pivote medial y ultra-congruente: satisfacción y resultados clínicos. Serie de casos / Medial and ultra-congruent pivot designed prosthesis: satisfaction and clinical results. case series

Introducción La artroplastia total de rodilla es un procedimiento exitoso que mejora significativamente la calidad de vida de los pacientes disminuyendo el dolor e incrementando su capacidad funcional. Sin embargo, la literatura reporta hasta 25% de pacientes insatisfechos. El objetivo de este estudio es presentar los resultados clínicos y la satisfacción de un grupo de pacientes operados con implantes de tipo pivote medial y ultra-congruente. Materiales y métodos Se realizó un estudio observacional retrospectivo. Se revisaron las historias clínicas de todos los pacientes operados con los sistemas mencionados con mínimo 12 meses post-operatorios. Se analizaron resultados de 100 rodillas (96 pacientes) que completaron los cuestionarios, con una media de seguimiento de 33.5 meses. Se aplicaron los cuestionarios KSS, KOOS y WOMAC. Se estudiaron diferencias en dolor y función entre la etapa pre-operatoria y el último seguimiento. Se analizó la satisfacción de los pacientes con respecto al dolor y la capacidad funcional. Se evaluaron complicaciones presentadas. Resultados Todos los criterios presentaron una mejora estadísticamente significativa entre la etapa pre-operatoria y el último seguimiento. 97% de los pacientes reportaron estar satisfechos con los resultados. Las medias de los cuestionarios fueron entre 83.97 y 95.3. Se presentó 1 caso de revisión por infección peri-protésica. Discusión Las prótesis de pivote medial y ultra-congruente constituyen opciones eficaces y seguras para el tratamiento de artrosis de rodilla. Es necesario realizar estudios prospectivos y comparativos que generen evidencia de más alto nivel para confirmar los beneficios de estos diseños.

Background Total knee arthroplasty is a successful procedure that improves patient quality of life by reducing pain and increasing their functional capacity. However, literature reports up to 25% dissatisfaction in patients. The objective of the study is to present the clinical results and satisfaction of a group of patients operated on using ultra-congruent medial pivot-type implants. Methods A retrospective observational study was carried out. The medical records of all the patients who underwent knee arthroplasty surgery with a specific system were reviewed, including patients with a minimum of 12 months follow up. An analysis was performed on the results of 100 knees (96 patients) that had completed questionnaires. There was a mean follow-up of 33.5 months. The KSS, KOOS, and WOMAC questionnaires were used. Differences in pain and function between the pre-surgical stage and the last follow-up were studied. An analysis was made on patient satisfaction with regard to pain and functional capacity. Specific complications were evaluated. Results All evaluation criteria showed a statistically significant improvement between the pre-surgical stage and the last follow-up. Almost all (97%) of patients reported being satisfied with the results. The means of the questionnaires were between 83.97 and 95.3. One case of revision due to peri-prosthetic infection was presented. Discussion Medial pivot and ultra-congruent prostheses designs are effective and safe options for the treatment of osteoarthritis of the knee. Prospective and comparative studies that generate higher level evidence are necessary to confirm the benefits of these designs.

Trastornos hipertensivos en el embarazo con infección urinaria / Hypertensive disorders of pregnancy associated with urinary tract infection

Objetivo: determinar la incidencia de los trastornos hipertensivos del embarazo en pacientes con infección del tracto urinario (ITU) en los Hospitales de San José e Infantil Universitario de San José, Bogotá, Colombia, en 2015. Materiales y métodos: cohorte de embarazadas que asistieron a urgencias con ITU que requirieron tratamiento intrahospitalario y seguimiento para establecer la ocurrencia de trastornos hipertensivos. La frecuencia de estos se describe sobre la base de incidencias acumuladas, así como en términos de la incidencia en cada nivel individual de gravedad de la ITU. Resultados: 138 embarazadas cumplieron con los criterios requeridos, edad media de 25 años (RIQ: 21-29), 42% cursaban el primer embarazo. El germen más aislado fue Escherichia coli. La incidencia de trastornos hipertensivos fue 21,7%. El trastorno más frecuente fue la preeclampsia y el tipo de ITU que más se presentó fue bacteriuria asintomática (35.5%). Conclusión: la ocurrencia de trastornos hipertensivos en embarazadas con infección del tracto urinario fue de 21,7%. Es importante investigar las infecciones del tracto urinario durante el embarazo como posibles factores generadores de preeclampsia

Objective: to present the basic mathematical, physical and radiological principles behind tractography, as well as, providing a review of the main tracts in the brain and their applications in neuroscience from the Fundación Universitaria de Ciencias de la Salud (FUCS) in Bogota D.C., Colombia experience. Materials and Methods: bibliographic review and use of a 1.5 T or 3T MR imaging system to describe tractography images in central nervous system disorders. Results: the main features of tractography are shown based on cases at our institution. Discussion: there are no identified studies on the usefulness of tractography in the vast majority of brain related pathologies. Although this procedure is currently available, clinical information is scarce, as the image-processing techniques are lengthy and in most institutions, protocols have not been determined to reconstruct each of the tracts in the brain. Conclusions: it is possible to reconstruct brain tracts using 1.5T and 3T scanners, identifying the major brain tracts and their relationship with brain tumors, cranioencephalic trauma, substance abuse and other conditio

Dolor protésico de rodilla en pacientes con baja probabilidad de infección y gammagrafía ósea positiva / Knee replacement pain in patients with low probability of infection and positive bone scintigraphy findings

Introducción Los estudios de medicina nuclear han sido omitidos en el abordaje diagnóstico de prótesis dolorosa con sospecha de infección por heterogeneidad de la evidencia y costo efectividad. Existen pacientes con baja probabilidad de infección y gammagrafía ósea de tres fases positiva, el objetivo del estudio fue evaluar el desenlace diagnóstico y terapéutico de estos pacientes. Materiales y métodos Estudio observacional serie de casos. Se seleccionaron pacientes con antecedente de RTR, dolor protésico posoperatorio y/o rigidez, baja probabilidad de infección, PCR y VSG negativa y gammagrafía ósea de 3 fases positiva. Se evaluó dolor pre y posoperatorio, la escala de Oxford para rodilla y la necesidad de cirugía de revisión. Resultados Se estudiaron 20 pacientes, promedio de seguimiento 42,1 meses. No se identificó infección o aflojamiento al final del seguimiento en ninguno de los casos. Al 25% se realizó revisión protésica secundario a (artrofibrosis, síndrome patelofemoral y dolor), este subgrupo tuvo una puntuación promedio de Oxford de 23.8 y EVA 7 al final del seguimiento, en los pacientes no reintervenidos la puntuación promedio de Oxford y EVA fue de 29 y 5 respectivamente. En el 70% de los pacientes no se estableció la causa del dolor protésico. Discusión El diagnóstico etiológico de una prótesis fallida es un reto. En pacientes con baja probabilidad de infección y gammagrafía ósea de tres fases positiva la infección como factor casual es poco probable. Pocos estudios describen el resultado de la gammagrafía ósea en pacientes con baja probabilidad de infección.

Background Nuclear medicine studies have been omitted in the diagnostic approach of painful bone replacements with suspicion of infection due to heterogeneity of evidence and cost effectiveness. There are patients with low probability of infection and positive three-stage bone scintigraphy, and the objective of the study was to evaluate the diagnostic and therapeutic outcome of these patients. Methods A retrospective case series study was carried out on Patients with a history of total Knee Replacement (TLR), postoperative prosthetic pain and / or stiffness, low probability of infection, and negative CRP-ESR results, and positive 3-phase bone scintigraphy were selected. Pre- and post-operative pain was included. The Oxford knee scale and the need for revision surgery were evaluated. Results A total of 20 patients were studied, with a mean follow-up of 42.1 months. There were no cases of infection or loosening identified at the end of follow-up. Twenty-five percent of the patients underwent prosthetic revision secondary to, arthrofibrosis, patellofemoral syndrome, and pain). An Oxford Knee Score of 23.8 and an average VAS of 7 was found, whereas the non-intervention group were 29 and 5, respectively. In 70% of patients, no aetiological diagnosis was established. Discussion The aetiological diagnosis of a failed prosthesis is a challenge. In patients with low probability of infection and positive three-stage bone scintigraphy infection as an aetiological factor is unlikely. Few studies describe the outcome of bone scintigraphy in patients with low probability of infection.

Normal Intracranial Translucency Values During the First Trimester of Gestation in a Latin American Population.

OBJECTIVES: The purpose of this study was to establish intracranial translucency reference values in healthy fetuses from a Latin American population. METHODS: This work was a cross-sectional retrospective correlational study. A review of sonographic reports from women between gestational ages of 11 weeks and 13 weeks 6 days at 2 health institutes in Bogota, Colombia, whose fetuses had a crown-rump length of 45 to 84 mm was conducted between January 1, 2010, and December 31, 2012. Women with multiple fetuses or with a deceased fetus were excluded. RESULTS: Data corresponding to 1520 obstetric sonographic examinations were included in the statistical analysis. The crown-rump length was between 45 and 84 mm, with a median of 65 mm (interquartile range, 58-73 mm). The median intracranial translucency was 1.7 mm (interquartile range, 1.4-2.2 mm). Different percentiles (1st, 5th, 10th, 25th, 50th, 75th, 90th, 95th, and 99th) were established for each crown-rump length value. A correlation between crown-rump length and intracranial translucency was found, which seemed to be linear. The intracranial translucency value was not significantly correlated with the frontomaxillary angle but was correlated with nuchal translucency, nasal bone length, and metopic suture length. CONCLUSIONS: We present normal intracranial translucency values in the first trimester of single gestations with live fetuses in a Latin American population. These values are similar to those described in other populations. The intracranial translucency value was linearly correlated with crown-rump length in fetuses between gestational ages of 11 weeks and 13 weeks 6 days, which is consistent with previous publications, although these data cannot be interpreted independently.

Morbimortalidad de gestantes con acretismo placentario análisis del protocolo de manejo del Hospital de San José, Bogotá DC / Maternal morbidity and mortality in cases of placenta accreta: A management protocol analysis Hospital de San José, Bogotá DC

Describir la morbimortalidad de gestantes con acretismo placentario en quienes se instauró el protocolo de manejo del Hospital de San José, Bogotá DC. Materiales y métodos: estudio observacional descriptivo retrospectivo en pacientes con acretismo placentario que se incluyeron en el protocolo de manejo del HSJ. No hubo criterios de exclusión. La base de datos se construyó en Excel 2007 y el análisis se realizó en STATA 10. Resultados: se incluyeron 29 pacientes con edad promedio de 34 años (DE 3.6). El 96,5% tenía antecedente quirúrgico. La estancia hospitalaria promedio fue de cinco días (DE 1.6). El 52% requirió transfusión de hemoderivados y en 10,3% fue masiva. El 17,2% cursaron con complicaciones derivadas del acto operatorio, siendo la infección y la coagulopatía de consumo las más comunes en el posoperatorio (4,1% y 8,3%). El 24,1% ingresaron a la UCI con estancia máxima de tres días, donde los soportes más requeridos fueron inotropía y ventilación mecánica (20,7% y 20,7%). No hubo mortalidad materna. Conclusiones: la instauración del protocolo para acretismo placentario en el Hospital de San José reflejó bajas estancias hospitalarias y pocas complicaciones e ingreso a la UCI, comparable con lo reportado en la literatura...

To describe maternal morbidity and mortality in cases of placenta accreta using Hospital de San José, Bogotá DC management protocol. Materials and Methods: a descriptive retrospective observational study of all cases of placenta accreta covered by the protocol used at HSJ to manage placent accreta. There were no exclusion criteria. Excel 2007 was used to create a database and STATA 10 for data analysis. Results: Twenty-nine patients with mean age 34 years (SD 3.6) were included. An antecedent history of surgical procedure was present in 96.5%. Average hospital stay was five days (SD 1.6). Fifty-two percent (52%) required blood products transfusion and 10.3% underwent a massive transfusion. Surgery - related complications occurred in 17.2%. Infection and disseminated intravascular coagulation were the most common postoperative complications (4.1% and 8.3%). Admission into the ICU was required in 24.1% with a maximum stay of 3 days. Inotropic support and mechanical ventilation (20.7% and 20.7%) were the most common forms of ICU support. There were no maternal deaths. Conclusions: the use of Hospital de San José placenta accreta management protocol resulted in short hospital stay and few complications and need of admission to the ICU compared to that reported in literature...